論文発表 Publications

論文発表 Publications

2025年度
  1. Oyama S, Matsunaga A, Takahashi H, Yamashita H, Ishizaka Y, Kaneko H.
    COVID-19-associated large-vessel vasculitis with elevated anti- angiotensin converting enzyme 2 antibody: three cases and a review of the literature. Clinical Rheumatology in press.
  2. Teratake Y, Okamura T, Ishizaka Y.
    SMAD5 phosphorylation by ALK1 is modulated by the interaction of the spike protein of SARS-CoV-2 and antiotensin-converting enzyme 2. Antiviral Res. 106261, 2025.


2024年度
  1. Kamoshida G, Yamaguchi D, Kaya, Y Yamakado T, Yamashita K, Aoyagi M, Nagai S, Yamada N, Yu Kawagishi, Sugano M, Sakairi Y, Ueno M, Takemoto N, Morita Y, Ishizaka Y, Yahiro. K.
    Development of a novel bacterial production system for recombinant bioactive proteins completely free from endotoxin contamination. Proc. Natl. Acad, Sci. USA, Nexus 3:328. 2024.


2023年度
  1. Takashina T, Matsunaga A, Shimizu Y, Sakuma T, Okamura T, Matsuoka K, Yamamoto T, Ishizaka Y.
    “Robust protein-based engineering of hepatocyte-like cells from human mesenchymal stem cells.” Hepatol Commun. (2023); 7 (3): e0051.
  2. Terada M, Saito S, Kutsuna S, Kinoshita-Iwamoto N, Togano T, Hangaishi A, Shiratori K, Takamatsu Y, Maeda K, Ishizaka Y, Ohtsu H, Satake M, Mitsuya H, Ohmagari N.
    Efficacy and safety of treatment with plasma from COVID-19-recovered individuals. Life, 2023 Nov 9;13(11):2184. doi: 10.3390/life13112184.
  3. Suzuki M, Matsunaga A, Miyoshi-Akiyama T, Terada -Hirashima J, Sadamasu K, Nagashima M, Takasaki J, Izumi S, Hojo M, Ishizaka Y, Sugiyama H.
    “Inhaled ciclesonide does not affect production of antibodies or elimination of virus in patients with COVID-19: Subanalysis of a multicenter, open-label randomized trial.” Drug Discov Ther. (2023); 17(5): 304-311. 10.5582/ddt.2023.01078.
  4. Matsunaga Akihiro, Ando Naokatsu, Yamagata Yuko, Shimura Mari , Gatanaga Hiroyuki , Oka Shinichi, Ishizaka Yukihito.
    Identification of viral protein R of human immunodeficiency virus-1 (HIV) and interleukin-6 as risk factors for malignancies in HIV-infected individuals. PLOS ONE, 19(1):e0296502. doi: 10.1371/journal.pone.0296502..
  5. Suzuki T, Asai Y, Takahashi K, SanadaM, Shimanishi Y, Terada M, Sato L, Inada M, Yamada G, Akiyama Y, Oshiro Y, Shiratori K, Togano , Takamatsu Y, Kenji M, Matsunaga A, Ishizaka Y, Nomoto H, Iwamoto N, Saito S, Kutsuna S, Morioka S, Ohmagari N.
    “Trends of participants in convalescent plasma donation for COVID-19 in Japan as the pandemic evolved.” Heliyon (2023); 9 (10): e20568. 10.1016/j.heliyon.2023.e20568.
  6. Saito S, Kutsuna S, Akifumi I, Hase R, Oda R, Terada J, Shimizu Y, Uemura Y, Takamatsu Y, Yasuhara A, Shiratori K, Satake M, Sakamoto N, Miyazaki Y, Shimizu H, Togano T, Matsunaga A, Okuma K, Hamaguchi I, Fujisawa K, Nagashima M, Ashida S, Terada M, Kimura A, Morioka S, Matsubayashi K, Tsuno NH, Kojima M, Kuramitsu M, Tezuka K, Ikebe E, Ishizaka Y, Kenji M, Hangaishi A, Mikami A, Sugiura W, Ohmagari N, Mitsuya H.
    Efficacy of convalescent plasma therapy for COVID-19 in Japan: An open-label, randomized, controlled trial. J Infect Chemother. 2023 May 11:S1341-321X(23)00122-8. doi: 10.1016/j.jiac.2023.05.012.
  7. Miyazato Y, Tsuzuki S, Matsunaga A, Morioka S, Terada M, Saito S, Iwamoto N, Kutsuna S, Ishizaka Y, Ohmagari N.
    Association between SARS-CoV-2 anti-spike antibody titers and the development of post-COVID conditions: a retrospective observational study. Global Health & Medicine Open, 30 (2): 106-111, 2023.


過去の論文発表

・Sato K, Misawa N, Iwami S, Satou Y, Matsuika M, Ishizaka Y, Ito M, Aihara K, An D-S, Koyanagi Y.
HIV-1 Vpr accelerates viral replication during acute infection by exploiting proliferating CD4+ T cells in vivo. PloS Pathogen, in press.

・Matsunaga A, Hishima T, Tanaka N, Yamazak M, Mochizuki M, Tanuma J, Oka S, Ishizaka Y, Shimura M and Hagiwara S.
DNA methylation profiling can classify HIV-associated lymphomas. AIDS, in press.

・Iijima K, Okudaira N, Tamura M, Saito Y, Shimura M, Goto M, Matsunaga A, Hoshino S, Kano S, Hagiwara S, Tanuma J, Gatanaga H, Baba M, Iguchi T, Yanagita M, Oka S, Okamura T and Ishizaka Y.
Retrotransposition of long interspersed element-1 in the kidney by human immunodeficiency virus type-1 Vpr. Retrovirology, 10:83, 2013.

・Richard J, Pham TN, Ishizaka Y, Cohen EA.
Viral protein R upregulates expression of ULBP2 on unifected bystander cells during HIV-1 infection of CD4+T lymphocytes. Virology 443:248-56, 2013.

・Matsuyama S, Matsunaga A, Sakamoto S, Iida Y, Suzuki Y, Ishizaka Y, Yamauchi K, Ishikawa T, Shimura M.
Metallomics. Scanning protein analysis of electrofocusing gels using X-ray fluorescence. Metallomics 5: 492-500, 2013 (DOI: 10.1039/C3MT20266F).

・Koyama T, Sun B, Tokunaga K, Tatsumi M and Ishizaka Y.
DNA damage aids human immunodeficiency virus type 1 infection by overcoming integrase inhibition. Retrovirology 10:21, 2013.

・Masaya Fukushi, Yoshiyuki Yoshinaka, Yusuke Matsuoka, Seisuke Hatakeyama, Yukihito Ishizaka, Teruo Kirikae, Takehiko Sasazuki, Tohru Miyoshi-Akiyama.
Monitoring S protein maturation in the endoplasmic reticulum by calnexin is important for the infectivity of severe acute respiratory syndrome-coronavirus. J. Virol. 86(21):11745-53, 2012 Nov;

・Noriyuki Okudaira, Tadashi Okamura, Masato Tamura, Kenta Iijma, Motohito Goto, Akihiro Matsunaga, Masako Ochiai, Hitoshi Nakagama, Shigeyuki Kano, Yoshiaki Fujii-Kuriyama and Yukihito Ishizaka.
Long interspersed element-1 is differentially regulated by food-borne carcinogens via the aryl hydrocarbon receptor. Oncogene, in press

・Koyama T, Shimura M, Minemoto Y, Nohara S, Shibata S, Iida Y, Iwashita S, Hasegawa M, Kurabayashi T, Hamada H, Kono K, Honda E, Aoki I, Ishizaka Y.
Evaluation of selective tumor detection by clinical magnetic resonance imaging using antibody-conjugated superparamagnetic iron oxide J. Cotrol. Release, 159: 413-8, 2012.

・Okudaira N, Goto M, Abe Y, Tamura M, An Y, Kano S, Ishizaka Y, Okamura T.
Involvement of retrotransposition of long interspersed nucleotide element-1 in DMBA/TPA-induced skin carcinogenesis. Cancer Sci. 102 (11): 2000-2006, 2011.

・Shimura M, Toyoda Y, Iijima K, Kinomoto M, Tokunaga K,Yoda K, Yanagida M, Sata T and Ishizaka Y.
Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation. J. Cell. Biol, 194: 721-35, 2011. Commentary in J. Cell. Biol 11/08/30.

・Uchida S, Watanabe N, Kudo Y, Yoshioka K, Matsunaga T, Ishizaka Y, Nakagama H, Poon RYC, and Yamashita K.
SCFβTrCP mediates stress-activated MAP kinase-induced Cdc25B degradation. J. Cell Sci. 124:2816-2825, 2011.

・Kono K, Nakashima S, Kokuryo D, Aoki I, Shimomoto H, Aoshima S, Maruyama K, Yuba E, Kojima C, Harada A, Ishizaka Y.
Multifunctional liposomes having temperature-triggered release and magnetic resonance imaging for tumor-specific chemotherapy. Biomaterials 32: 1387-1395, 2011

・奥平准之、石坂幸人.
難病発症に関わる内在性レトロエレメントの活性化とその機構. 日本生化学会誌、84, 870-874, 2012

・Ishizaka Y, Okudaira N, Tamura M, Iijima K, Shimura M, Goto M, Okamura T.
Modes of retrotransposition of long interspersed element-1 by environmental factors. Front Microbiol. 3:191, 2012. Epub 2012 May 31.

・Ishizaka Y, Okudaira N, Okamura T.
2012 Regulation of retrotransposition of long interspersed element-1 by mitogen-activated protein kinases. pp 187-198. In Gabriela Da Silva Xavier (ed), Protein Kinases / Book 1, InTech - Open Access Publisher, Croatia. http://www.intechopen.com/books/protein-kinases

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